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A “Trojan horse” bispecific antibody strategy for broad protection against ebolaviruses→
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Wec AZ et al, Science 2016
Read MoreA Single Residue in Ebola Virus Receptor NPC1 Influences Cellular Host Range in Reptiles→
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Ndungo E et al, mSphere 2016
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Direct Visualization of Ebola Virus Fusion Triggering in the Endocytic Pathway→
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Spence JS et al, mBio 2016
Read MoreBispecific Antibody Affords Complete Post-Exposure Protection of Mice from Both Ebola (Zaire) and Sudan Viruses→
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Frei JC, Nyakatura EK, et al, Sci Rep 2016
Read MoreCysteine cathepsin inhibitors as anti-Ebola agents→
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Read MoreFilovirus receptor NPC1 contributes to species-specific patterns of ebolavirus susceptibility in bats→
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Ng M, Ndungo E, Kaczmarek ME et al, eLife 2015
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Niemann-Pick C1 Is essential for ebolavirus replication and pathogenesis in vivo→
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Synthetic antibodies with a human framework that protect mice from lethal Sudan ebolavirus challenge→
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Chen G, Koellhoffer JF, Zak SE et al, ACS Chem Biol 2014
Read MoreComprehensive functional analysis of N-linked glycans on Ebola virus GP1→
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Read MoreC-Peptide inhibitors of Ebola virus glycoprotein-mediated cell entry: Effects of conjugation to cholesterol and side chain-side chain cross linking→
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Read MoreConformational properties of peptides corresponding to the ebolavirus GP2 membrane-proximal external region in the presence of micelle-forming surfactants and lipids→
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Read MoreA mutation in the Ebola virus envelope glycoprotein restricts viral entry in a host species and cell-type specific manner→
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Martinez O et al, J Virol 2013
Read MoreEndocytic pathways involved in filovirus entry: advances, implications and future directions→
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Bhattacharyya S et al, Viruses 2012
Read MoreTwo synthetic antibodies that recognize and neutralize distinct proteolytic forms of the Ebola virus envelope glycoprotein→
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Read MoreNPC1/NPC1-like1 Chimeras Define Sequences Critical for NPC1’s Function as a Filovirus Entry Receptor→
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