September 08, 2016

A “Trojan horse” bispecific antibody strategy for broad protection against ebolaviruses→

September 08, 2016/ Kartik Chandran

A “Trojan horse” bispecific antibody strategy for broad protection against ebolaviruses

Wec AZ et al, Science 2016

May 05, 2016

Antibody Treatment of Ebola and Sudan Virus Infection via a Uniquely Exposed Epitope within the Glycoprotein Receptor-Binding Site→

May 05, 2016/ Kartik Chandran

Antibody Treatment of Ebola and Sudan Virus Infection via a Uniquely Exposed Epitope within the Glycoprotein Receptor-Binding Site

Howell KA et al, Cell Rep 2016

March 30, 2016

A Single Residue in Ebola Virus Receptor NPC1 Influences Cellular Host Range in Reptiles→

March 30, 2016/ Kartik Chandran

A Single Residue in Ebola Virus Receptor NPC1 Influences Cellular Host Range in Reptiles

Ndungo E et al, mSphere 2016

February 23, 2016

Host-primed Ebola virus GP exposes a hydrophobic NPC1 receptor-binding pocket, revealing a target for broadly neutralizing antibodies→

February 23, 2016/ Kartik Chandran

Host-primed Ebola virus GP exposes a hydrophobic NPC1 receptor-binding pocket, revealing a target for broadly neutralizing antibodies

Bornholdt ZA et al, mBio 2016

February 09, 2016

Direct Visualization of Ebola Virus Fusion Triggering in the Endocytic Pathway→

February 09, 2016/ Kartik Chandran

Direct Visualization of Ebola Virus Fusion Triggering in the Endocytic Pathway

Spence JS et al, mBio 2016

January 29, 2016

Bispecific Antibody Affords Complete Post-Exposure Protection of Mice from Both Ebola (Zaire) and Sudan Viruses→

January 29, 2016/ Kartik Chandran

Bispecific Antibody Affords Complete Post-Exposure Protection of Mice from Both Ebola (Zaire) and Sudan Viruses

Frei JC, Nyakatura EK, et al, Sci Rep 2016

January 20, 2016

Cysteine cathepsin inhibitors as anti-Ebola agents→

January 20, 2016/ Kartik Chandran

Cysteine cathepsin inhibitors as anti-Ebola agents

van der Linden W et al, ACS Infect Dis 2016