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A “Trojan horse” bispecific antibody strategy for broad protection against ebolaviruses→
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Wec AZ et al, Science 2016
Read MoreA Single Residue in Ebola Virus Receptor NPC1 Influences Cellular Host Range in Reptiles→
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Ndungo E et al, mSphere 2016
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Direct Visualization of Ebola Virus Fusion Triggering in the Endocytic Pathway→
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Spence JS et al, mBio 2016
Read MoreBispecific Antibody Affords Complete Post-Exposure Protection of Mice from Both Ebola (Zaire) and Sudan Viruses→
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Frei JC, Nyakatura EK, et al, Sci Rep 2016
Read MoreCysteine cathepsin inhibitors as anti-Ebola agents→
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Read MoreFilovirus receptor NPC1 contributes to species-specific patterns of ebolavirus susceptibility in bats→
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Ng M, Ndungo E, Kaczmarek ME et al, eLife 2015
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Niemann-Pick C1 Is essential for ebolavirus replication and pathogenesis in vivo→
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Herbert AS et al, MBio 2015
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Conformational properties of peptides corresponding to the ebolavirus GP2 membrane-proximal external region in the presence of micelle-forming surfactants and lipids→
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Regula LK, Harris R et al, Biochemistry 2013
Read MoreTwo synthetic antibodies that recognize and neutralize distinct proteolytic forms of the Ebola virus envelope glycoprotein→
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Koellhoffer JF, Chen G et al, Chembiochem 2012
Read MoreNPC1/NPC1-like1 Chimeras Define Sequences Critical for NPC1’s Function as a Filovirus Entry Receptor→
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Krishnan A et al, Viruses 2012
Read MoreCrystal Structure of the Marburg virus GP2 core domain in its post-fusion conformation→
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Koellhoffer JF et al, Biochemistry 2012
Read MoreStructural basis for differential neutralization of ebolaviruses→
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Bale S, Dias JM et al, Viruses 2012
Read MoreEbola virus entry requires the host-programmed recognition of an intracellular receptor→
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Miller EH, Obernosterer G, Raaben M, Herbert AS et al, EMBO J 2012
Read MoreMarburg Virus Glycoprotein GP2: pH-Dependent Stability of the Ectodomain Alpha-Helical Bundle→
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Harrison JS et al, Biochemistry 2012
Read MoreFiloviruses require endosomal cysteine proteases for entry but display distinct protease preferences→
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